Best Practice & Research Clinical Rheumatology
Volume 21, Issue 1 , Pages 77-91, February 2007

Low back pain (non-specific)

  • M. van Tulder, PhD (Professor of Health Technology Assessment)

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +31 20 5988 178.
  • The Low Back Pain Group of the Bone and Joint Health Strategies for Europe Project

Department of Orthopaedic Surgery, Innsbruck Medical University, Anichstrasse 35, A-6020 Innsbruck, Austria

Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam

Institute of Health Sciences, De Boelelaan 1081, 1081 HV, Vrije Universiteit Amsterdam, The Netherlands

Low back pain (LBP) is defined as pain localised between the 12th rib and the inferior gluteal folds, with or without leg pain. Most cases are non-specific, but in about 10% of cases a specific cause is identified. Red flags are typical signs or symptoms that are frequently associated with specific LBP. Yellow flags are prognostic factors associated with a more unfavourable and often chronic disabling course of the disease. LBP has a lifetime prevalence of 60–85%. At any one time, about 15% of adults have LBP. LBP poses an economic burden to society, mainly in terms of the large number of work days lost (indirect costs) and less so by direct treatment costs. A substantial proportion of individuals with chronic LBP has been found to have chronic widespread pain. LBP is often associated with other pain manifestations such as headache, abdominal pain and pain in different locations of the extremities. Widespread pain is associated with a worse prognosis compared to localised LBP.

Treatment targets are reduction of pain and better activity/participation, including prevention of disability as well as maintainance of work capacity. The evidence from selected and appraised guidelines, systematic reviews and major clinical studies was classified into four levels, level Ia being the best level with evidence from meta-analysis of randomised controlled trials.

Key recommendations (level Ia): fitness programmes and advice to stay active can reduce pain, improve function and can prevent LBP becoming chronic. Simple analgesics, NSAIDs and muscle relaxants can reduce pain and can improve and maintain function. Maintaining physical activity, avoiding rest and manual therapy can reduce pain and maintain and restore function in acute LBP. Behavioural treatment can prevent LBP becoming chronic. Aerobic fitness and endurance training, behavioural treatment and multi-disciplinary treatment programmes can reduce pain and can improve/maintain function in chronic LBP.

Key words: low back pain, non-specific, treatment, guidelines

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PII: S1521-6942(06)00108-2

doi:10.1016/j.berh.2006.08.004

Best Practice & Research Clinical Rheumatology
Volume 21, Issue 1 , Pages 77-91, February 2007