Best Practice & Research Clinical Rheumatology
Volume 20, Issue 6 , Pages 1139-1157, December 2006

Viral causes of arthritis

  • Rauli Franssila, MD, PhD (Research Fellow)

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +358 9 1912 6676; Fax: +358 9 1912 6491.
    • ,
  • Klaus Hedman, MD (Professor of Virology)

Department of Virology, Haartman Institute, University of Helsinki and HUCH Laboratory Division, Haartmaninkatu 3, FI-00290 Helsinki, Finland

Several viruses cause postinfectious arthritis. The disease is a typical manifestation of arthritogenic alphaviruses, rubella virus and human parvovirus B19. In addition, arthritis is not uncommon after infection by HIV, cytomegalovirus, hepatitis B virus, hepatitis C virus, or Epstein–Barr virus (EBV). Also prolonged arthritis may result from viral infections, particularly with alphaviruses and human parvovirus B19. Viruses such as EBV and B19 may have significant roles in initiating chronic arthropathies, which in some cases may be indistinguishable from rheumatoid arthritis.

Key words: arthritis, virus, autoimmunity, pathogenesis

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PII: S1521-6942(06)00111-2

doi:10.1016/j.berh.2006.08.007

Best Practice & Research Clinical Rheumatology
Volume 20, Issue 6 , Pages 1139-1157, December 2006

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