Best Practice & Research Clinical Rheumatology
Volume 21, Issue 5 , Pages 827-840, October 2007

Measuring disability and quality of life in established rheumatoid arthritis

  • Tore K. Kvien, MD, PhD (Professor)

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Rheumatology, Diakonhjemmet Hospital, Box 23 Vinderen, N-0319 Oslo, Norway. Tel.: +47 22 45 17 50; Fax: +47 22 45 17 78.

Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

Department of Rheumatology, Diakonhjemmet Hospital and Faculty of Medicine, University of Oslo, Norway

Rheumatoid arthritis is a chronic inflammatory disease with a major impact on physical and psychological health. It can cause severe disability and reduce health-related quality of life, aspects that are important to patients. Thus, it is important to measure disability and health-related quality of life in clinical practice and in clinical trials. This article presents an overview of the most important measures of outcome concerning disability and health-related quality of life, including different forms of the Health Assessment Questionnaire (HAQ, MHAQ, MDHAQ, HAQ II), visual analogue scales for fatigue and function, SF-36, Arthritis Impact Measurement Scales (AIMS/AIMS2), the Rheumatoid Arthritis Quality of Life (RAQoL) questionnaire, Nottingham Health Profile, Sickness Impact Profile and the utility instruments 15D, EQ-5D, SF-6D and Health Utilities Index (HUI) 2 and 3.

Key words: disability, health-related quality of life, rheumatoid arthritis, utility

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PII: S1521-6942(07)00060-5

doi:10.1016/j.berh.2007.05.004

Best Practice & Research Clinical Rheumatology
Volume 21, Issue 5 , Pages 827-840, October 2007