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Best Practice & Research Clinical Rheumatology
Volume 21, Issue 6
, Pages 1037-1049
, December 2007
Mixed connective tissue disease: what is behind the curtain?
References
- Mixed connective tissue disease – an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). American Journal of Medicine. 1972;52:148–159
- Association of antibodies to ribonucleoprotein and Sm antigens with mixed connective-tissue disease, systematic lupus erythematosus and other rheumatic diseases. The New England Journal of Medicine. 1976;295:1149–1154
- . Mixed connective tissue disease – goodbye to all that. British Journal of Rheumatology. 1992;31:695–700
- . Shared autoimmunity: a concept for which the time has come. Autoimmunity. 2005;38:201–203
- Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. The Journal of Clinical Investigation. 1998;101:273–281
- . Autoantibodies in polymyositis. Rheumatic Disease Clinics of North America. 1992;18:455–482
- Polymyositis, pulmonary fibrosis and autoantibodies to aminoacyl-tRNA synthetase enzymes. The Quarterly Journal of Medicine. 1990;77:1019–1038
- . Myositis-specific autoantibodies: overview and recent developments. Current Opinion In Rheumatology. 2001;13:476–482
- Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Annals of the Rheumatic Diseases. 2007;66:754–763
- Correlates between autoantibodies to nucleolar antigens and clinical features in patients with systemic sclerosis (scleroderma). Arthritis & Rheumatism. 1988;31:525–532
- . Autoantibodies in systemic sclerosis. Seminars in Arthritis and Rheumatism. 2005;35:35–42
- Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma. The Journal of Clinical Investigation. 1996;98:785–792
- Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. The New England Journal of Medicine. 2006;354:2667–2676
- Anti-endothelial cell antibodies from patients with limited cutaneous systemic sclerosis bind to centromeric protein B (CENP-B). Clinical Immunology. 2006;120:212–219
- . Correlation of serum anti-DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis. Arthritis & Rheumatism. 2003;48:1363–1373
- . DNA topoisomerase I binding to fibroblasts induces monocyte adhesion and activation in the presence of anti-topoisomerase I autoantibodies from systemic sclerosis patients. Arthritis & Rheumatism. 2006;54:963–973
- Direct binding of anti-DNA topoisomerase I autoantibodies to the cell surface of fibroblasts in patients with systemic sclerosis. Arthritis & Rheumatism. 2004;50:3265–3274
- Early undifferentiated connective tissue disease (CTD). VI. An inception cohort after 10 years: disease remissions and changes in diagnoses in well established and undifferentiated CTD. The Journal of Rheumatology. 1999;26:816–825
- Five-year follow-up of 665 Hungarian patients with undifferentiated connective tissue disease (UCTD). Clinical and Experimental Rheumatology. 2003;21:313–320
- Undifferentiated connective tissue disease: analysis of 83 patients with a minimum follow up of 5 years. The Journal of Rheumatology. 2002;29:2345–2349
- Incomplete lupus erythematosus: results of a multicentre study under the supervision of the EULAR Standing Committee on International Clinical Studies Including Therapeutic Trials (ESCISIT). Rheumatology (Oxford). 2001;40:89–94
- Frequency and clinical significance of antibodies to ribonucleoprotein in SLE and other connective tissue disease subgroups. Annals of the Rheumatic Diseases. 1977;36:442–447
- Quantitation of anti-RNP and anti-Sm antibodies in MCTD and SLE patients by immunoblotting. Clinical and Experimental Immunology. 1985;59:457–466
- . Predominance of IgM anti-U1RNP antibodies in patients with systemic lupus erythematosus. British Journal of Rheumatology. 1996;35:534–541
- Follow-up of 151 patients with high-titer U1RNP antibodies. Clinical Rheumatology. 1996;15:254–260
- . Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America. 1979;76:5495–5499
- . Clinical manifestations and anti-(U1)snRNP antibodies: a prospective study of 29 anti-RNP antibody positive patients. British Journal of Rheumatology. 1992;31:811–817
- Autoantibodies specific for apoptotic U1-70K are superior serological markers for mixed connective tissue disease. Arthritis Research & Therapy. 2005;7:R302–R309
- . Apoptotic U1-70 kd is antigenically distinct from the intact form of the U1-70-kd molecule. Arthritis & Rheumatism. 2002;46:1264–1269
- Endothelial cell-binding activity of anti-U1-ribonucleoprotein antibodies in patients with connective tissue diseases. Clinical and Experimental Immunology. 2001;126:345–354
- Increase of cytokine production by pulmonary artery endothelial cells induced by supernatants from monocytes stimulated with autoantibodies against U1-ribonucleoprotein. Clinical and Experimental Rheumatology. 1999;17:705–712
- Scleroderma-like nailfold capillaroscopic abnormalities are associated with anti-U1-RNP antibodies and Raynaud's phenomenon in SLE patients. Lupus. 2002;11:35–41
- . Autoantibodies to the URNP particles: relationship to clinical diagnosis and nephritis. Clinical and Experimental Immunology. 1991;83:286–290
- A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Arthritis & Rheumatism. 2006;54:661–669
- Long-term outcome in mixed connective tissue disease: longitudinal clinical and serologic findings. Arthritis & Rheumatism. 1999;42:899–909
- Evaluation of interstitial lung disease in mixed connective tissue disease (MCTD). Rheumatology (Oxford). 2005;44:656–661
- . Characteristics of patients with serum antibodies to extractable nuclear antigens. Arthritis & Rheumatism. 1976;19:851–856
- . Clinical significance of antibodies to ribonucleoprotein. Annals of the Rheumatic Diseases. 1979;38:74–78
- . Mixed connective tissue disease: to be or not to be?. Arthritis & Rheumatism. 1998;41:768–777
- . Antibodies to components of extractable nuclear antigen. Clinical characteristics of patients. Archives of Internal Medicine. 1976;136:425–431
- Long-term follow-up of 46 patients with anti-(U1)snRNP antibodies. British Journal of Rheumatology. 1994;33:1117–1120
- . Lungs in mixed connective tissue disease. Journal of Thoracic Imaging. 1992;7:55–61
- . Articular manifestations of mixed connective tissue disease. Arthritis & Rheumatism. 1979;22:43–51
- . Patients with arthritis and anti-U1-RNP antibodies: a 10-year follow-up. British Journal of Rheumatology. 1990;29:345–348
- . Mixed connective tissue disease – clinical and radiological aspects of 20 cases. British Journal of Radiology. 1977;50:620–625
- Anticyclic citrullinated peptide antibodies in patients with mixed connective tissue disease. Modern Rheumatology. 2004;14:367–375
- HLA type as a predictor of mixed connective tissue disease differentiation. Ten-year clinical and immunogenetic followup of 46 patients. Arthritis & Rheumatism. 1995;38:259–266
- A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis. Arthritis Research & Therapy. 2004;6:R303–R308
- Pathology of skeletal muscle in mixed connective tissue disease. Arthritis & Rheumatism. 1977;20:985–988
- . Mixed connective tisssue disease: a clinicopathologic study of 20 cases. Seminars in Arthritis and Rheumatism. 1980;10:25–51
- . Muscle involvement in mixed connective tissue disease. Rheumatic Disease of Clinics North America. 2005;31:509–517vii
- Mapping of epitopes on U1 snRNP polypeptide A with synthetic peptides and autoimmune sera. Clinical and Experimental Immunology. 1991;86:71–78
- Anti-A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease. The Journal of Clinical Investigation. 1997;100:127–135
- MICA4/HLA-DRB1*04/TNF1 haplotype is associated with mixed connective tissue disease in Swedish patients. Human Immunology. 2003;64:290–296
- Human autoantibodies against the 70-kd polypeptide of U1 small nuclear RNP are associated with HLA-DR4 among connective tissue disease patients. Arthritis & Rheumatism. 1990;33:666–673
- More evidence of distinctive features of mixed connective tissue disease. Scandinavian Journal of Rheumatology. 1993;22:63–68
- Difference in HLA-linked genetic background between mixed connective tissue disease and systemic lupus erythematosus. Tissue Antigens. 1993;41:20–25
- Differences in HLA antigens between patients with mixed connective tissue disease and systemic lupus erythematosus. Annals of the Rheumatic Diseases. 1992;51:52–55
- Molecular genetic analysis of HLA-DR and HLA-DQ genes among anti-U1-70-kd autoantibody positive connective tissue disease patients. Arthritis & Rheumatism. 1992;35:83–94
- HLA and immunoglobulin allotypes in mixed connective tissue disease. Arthritis & Rheumatism. 1988;31:131–134
- HLA-DR4 and Gm(1,3;5,21) are associated with U1-nRNP antibody positive connective tissue disease. Annals of the Rheumatic Diseases. 1987;46:189–196
- . Comparative study of 4 diagnosis criteria sets for mixed connective tissue disease in patients with anti-RNP antibodies. Autoimmunity Group of the Hospitals of Toulouse. The Journal of Rheumatology. 1996;23:2055–2062
- . Classification and diagnostic criteria for mixed connective tissue disease. In: Kasukawa R, Sharp GC editor. Mixed connective tissue diseases and antinuclear antibodies. Amsterdam: Elsevier; 1987;p. 41–47
- . Does mixed connective tissue disease exist? Yes. Rheumatic Disease Clinics of North America. 2005;31:411–420
- . Raynaud's phenomenon in mixed connective tissue disease. Rheumatic Disease of Clinics North America. 2005;31:465–481vi
- . Other manifestations of mixed connective tissue disease. Rheumatic Disease Clinics of North America. 2005;31:519–533vii
- . Pulmonary vascular manifestations of mixed connective tissue disease. Rheumatic Disease Clinics of North America. 2005;31:451–464vi
- Fatal sinus vein thrombosis in a patient with mixed connective tissue disease and secondary antiphospholipid antibody syndrome. Medizinische Klinik (Munich). 2001;96:361–364
- Most anticardiolipin antibodies in mixed connective tissue disease are beta2-glycoprotein independent. The Journal of Rheumatology. 1998;25:189–190
- . Mixed connective tissue disease. Lupus. 2006;15:132–137
- Renal involvement in mixed connective tissue disease: a longitudinal clinicopathologic study. Seminars in Arthritis and Rheumatism. 1986;16:135–145
- . Treatment of mixed connective tissue disease. Rheumatic Disease Clinics of North America. 2005;31:549–565viii
- . Inflammatory myopathy associated with mixed connective tissue disease and scleroderma renal crisis. Muscle & Nerve. 2001;24:1562–1566
- A prospective evaluation emphasizing pulmonary involvement in patients with mixed connective tissue disease. Medicine (Baltimore). 1984;63:92–107
- Myocarditis of mixed connective tissue disease: favourable outcome after intravenous pulsed cyclophosphamide. Clinical Rheumatology. 1999;18:85–87
- . Transverse myelitis, a rare neurological manifestation of mixed connective tissue disease – a case report and a review of literature. Clinical Rheumatology. 2007;26:445–447
- . Efficacy of pulsed intravenous immunoglobulin therapy in mixed connective tissue disease. Journal of American Academy of Dermatology. 2002;46:123–127
- Fasciitis in mixed connective tissue disease successfully treated with high-dose intravenous immunoglobulin. Internal Medicine. 2003;42:910–911
- . Tumor necrosis factor-alpha antagonists induce lupus-like syndrome in patients with scleroderma overlap/mixed connective tissue disease. The Journal of Rheumatology. 2003;30:2725–2727
- . Prostaglandin infusion therapy for intermittent digital ischemia in a patient with mixed connective tissue disease. Case report and review of the literature. Journal of American Academy of Dermatology. 1989;20:893–897
PII: S1521-6942(07)00110-6
doi: 10.1016/j.berh.2007.10.002
© 2007 Elsevier Ltd. All rights reserved.
« Previous
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Best Practice & Research Clinical Rheumatology
Volume 21, Issue 6
, Pages 1037-1049
, December 2007
