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Best Practice & Research Clinical Rheumatology
Volume 22, Issue 2
, Pages 253-267
, April 2008
Animal models for arthritis
References
- . Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences of the United States of America. 1992;89:9784–9788
- Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis & Rheumatism. 1993;36:1681–1690
- Il-1ab blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation. Journal of Immunology. 1999;163:5049–5055
- Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis & Rheumatism. 1998;41:2196–2204
- A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. The New England Journal of Medicine. 2000;343:1586–1593
- New therapies for treatment of rheumatoid arthritis. Lancet. 2007;370:1861–1874
- Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. American Journal of Pathology. 2005;167:141–149
- Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis & Rheumatism. 2006;54:2817–2829
- CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathway. Arthritis & Rheumatism. 2006;54:765–778
- . Immunopathogenesis of collagen arthritis. Springer Seminars in Immunopathology. 2003;25:3–18
- . Animal models of rheumatoid and their relevance to human disease. Pathophysiology. 2005;12:167–181
- . Animal models of arthritis caused by systemic alteration of the immune system. Current Opinion In Immunology. 2005;17:589–594
- . Modeling human arthritic diseases in non-human primates. Arthritis Research & Therapy. 2005;7:145–154
- Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. American Journal of Pathology. 1996;149:1607–1615
- Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis. Arthritis & Rheumatism. 2005;52:1999–2002
- Methotrexate and albumin coupled with MTX supress synovial fibroblast invasion and cartilage degradation in vivo. Annals of the Rheumatic Diseases. 2004;63:884–886
- Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway. Gene Therapy. 2002;9:1508–1519
- Analysis of the kinetics of osteoclastogenesis in arthritic rats. Arthritis & Rheumatism. 2005;52:3192–3201
- Tenosynovitis and osteoclast formation as the initial preclinical changes in a murine model of inflammatory arthritis. Arthritis & Rheumatism. 2007;56:79–88
- IL-1 mediates TNF-induced osteoclastogenesis. The Journal of Clinical Investigation. 2005;115:282–290
- RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis. Journal of Bone and Mineral Research. 2005;20:1757–1765
- M-CSF mediated TNF-induced inflammatory osteolysis. The Journal of Clinical Investigation. 2005;115:3418–3427
- Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody. Biochemical and Biophysical Research. 2006;347:124–132
- Additive bone protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models. Arthritis & Rheumatism. 2005;52:1604–1611
- Efficacy of imatinib mesylate (ST1571) treatment for a patient with rheumatoid arthritis developing chronic myelogenous leukema. Clinical Rheumatology. 2003;22:329–332
- Macrophage colony stimulating factor receptor, c-fms, is a novel target of imatinib. Blood. 2005;105:3127–3132
- Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis. Journal of Bone and Mineral Research. 2006;24:274–282
- Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis. The Journal of Clinical Investigation. 2006;116:2633–2644
- Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis. Arthritis & Rheumatism. 2006;54:1410–1414
- Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis. Journal of Immunology. 2000;164:5922–5927
- Vegfb gene knock-out mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis. Arthritis & Rheumatism. 2003;48:2660–2669
- Relationship between angiogenesis and inflammation in experimental arthritis. European Cytokine Network. 2006;17:202–210
- Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis. American Journal of Pathology. 2004;165:2087–2098
- Analysis of vascular gene expression in arthritic synovium by laser-mediated microdissection. Arthritis & Rheumatism. 2007;56:1094–1105
- . Adenoviral delivery of soluble VEGF receptor 1 abrogates disease activity in murine collagen-induced arthritis. Gene Therapy. 2003;10:1950–1960
- Arginine-rich anti-vascular endothelial growth factor (anti-VEGF) hexapeptide inhibits collagen-induced arthritis and VEGF-stimulated productions of TNF-alpha and IL-6 by human monocytes. Journal of Immunology. 2005;174:5846–5855
- Neutralisation of vascular endothelial growth factor prevents collagen-induced arthritis and ameliorates established disease in mice. Biochemical and Biophysical Research. 2001;281:562–568
- Amelioration of collagen-induced arthritis in rats by nanogold. Arthritis & Rheumatism. 2007;56:544–554
- Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis. Molecular Therapy. 2002;5:547–554
- Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis. Arthritis & Rheumatism. 2002;46:793–801
- Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis. Arthritis & Rheumatism. 2005;52:339–344
- . Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation. Annals of the Rheumatic Diseases. 2006;65:1414–1421
- . Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy and corneal diseases. Glycobiology. 2002;12:107–116
- Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. FASEB Journal. 2002;16:673–680
- Accelerated, aging-dependent development of osteoarthritis in alpha1 integrin-deficient mice. Arthritis & Rheumatism. 2003;48:2873–2880
- Absence of the alpha1(IX) chain leads to a functional knock-out of the entire collagen IX protein in mice. The Journal of Biological Chemistry. 1997;272:20650–20654
- Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen. Arthritis & Rheumatism. 2006;54:2891–2900
- Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging. Osteoarthritis and Cartilage. 2005;13:66–73
- Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease. Proceedings of the National Academy of Sciences of the United States of America. 2005;102:11740–11745
- BMP receptor signalling is required for postnatal maintenance of articular cartilage. PLoS Biology. 2004;2:e355
- Osteoarthritis development in novel experimental mouse models induced by knee joint instability. Osteoarthritis and Cartilage. 2005;13:632–641
- Knee cartilage thickness measurements using MRI: a 4 1/2 month longitudinal study in the meniscectomized guinea pig model of OA. Osteoarthritis and Cartilage. 2007;15:656–665
- Early detection and monitoring of cartilage alteration in the experimental meniscectomised guinea pig model of osteoarthritis by 99mTc-NTP 15-5 scintigraphy. European Journal of Nuclear Medicine and Molecular Imaging. 2007;34:1280–1290
- Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Arthritis & Rheumatism. 2006;54:2462–2470
- Characterizsation of pro-apoptotic and matrix-degenerative gene expression following induction of osteoarthritis in mature and aged rabbits. Osteoarthritis and Cartilage. 2006;14:471–476
- Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. Arthritis Research & Therapy. 2007;9:R13
- Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like pain and secondary hyperalgesia. Osteoarthritis and Cartilage. 2006;14:1041–1048
- Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised-controlled clinical trial. Lancet. 2001;357:251–256
- Effect of oral glucosamine on cartilage degradation in a rabbit model of osteoarthritis. Arthritis & Rheumatism. 2005;52:1118–1128
- . Hyaluronans in the treatment of osteoarthritis of the knee: evidence for a disease-modifying activity. Osteoarthritis and Cartilage. 2005;13:216–224
- Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis. Arthritis & Rheumatism. 2002;46:694–703
- The therapeutic effects of basic fibroblast growth factor contained in gelatine hydrogel microspheres on experimental osteoarthritis in the rabbit knee. Arthritis & Rheumatism. 2006;54:264–270
- . Development of osteoarthritic lesions in mice by metabolic and mechanical alterations in knee joints. American Journal of Pathology. 1989;135:1001–1014
- Monoiodoacetate induced experimental osteoarthritis. Arthritis & Rheumatism. 1997;40:1670–1679
- . Validation of a chemical osteoarthritis model in rabbit temporomandibular joint: a compliment to biomechanical models. International Journal of Oral and Maxillofacial Surgery. 2006;35:1026–1033
- Development and pharmacological characterization of a rat model of osteoarthritis pain. Pain. 2005;114:339–346
- . Antinociceptive efficacy of lacosamide in the monosidum iodoacetate rat model for osteoarthritis pain. Arthritis Research & Therapy. 2007;9:R14
- . Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor ß/bone morphogenetic protein inhibitors during experimental osteoarthritis. Arthritis & Rheumatism. 2003;48:3442–3451
- Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease. Osteoarthritis and Cartilage. 2007;15:1190–1198
- Regeneration of defects in articular cartilage in rat knee joints by CCN 2. Journal of Bone and Mineral Research. 2004;19:1308–1319
- Gene transfer with HSP70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis. FASEB Journal. 2006;20:65–75
- . Immunohistologic demonstration of platelet-derived growth factor and sis-conogene expression in scleroderma. The Journal of Investigation Dermatology. 1989;92:201–203
- Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts. The Journal of Experimental Medicine. 1992;175:1227–1234
- Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis & Rheumatism. 2007;56:311–322
- . Imatinib for the treatment of pulmonary arterial hypertension. The New England Journal of Medicine. 2005;353:1412–1413
- Macrophage migration inhibitory factor deficiency attenuates macrophage recruitment, glomerulonephritis, and lethality in MRL/lpr mice. Journal of Immunology. 2006;177:5687–5696
- Inhibition of B-cell death causes the development of an IgA nephropathy in (New Zealand White
×
C57BL/6)F1-bcl-2 transgenic mice. Journal of Immunology. 2004;172:7177–7185 - CD4
+
CD25
+
T cell-dependent inhibition of autoimmunity in transgenic mice overexpressing human Bcl-2 in T-lymphocytes. Journal of Immunology. 2007;178:2778–2786 - Autoimmunity as a result of escape from RNA surveillance. Journal of Immunology. 2006;177:1698–1707
- Immunization with short peptides from the 60-kDa Ro antigen recapitulates the serological and pathological findings as well as the salivary gland dysfunction of Sjögren's syndrome. Journal of Immunology. 2005;175:8409–8414
- . Animal models of HLA-B27 associated diseases: new outcomes. Joint Bone Spine. 2006;73:132–138
- Defective costimulatory function is a striking feature of antigen-presenting cells in an HLA-B27-transgenic rat model of spondyloarthropathy. Arthritis & Rheumatism. 2004;50:1624–1635
- HLA-B27 misfolding in transgenic rats is associated with the activation of the unfolded protein response. Journal of Immunology. 2005;175:2438–2448
- Inflammatory disease in HLA-B27 transgenic rats. Immunological Reviews. 1999;169:209–223
- Additional human ß2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats. Arthritis & Rheumatism. 2006;54:1317–1327
- Mice lacking endogenous major histocompatibility complex class II develop arthritis resembling psoriatic arthritis at an advanced age. Arthritis & Rheumatism. 2002;46:2465–2475
- . Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: expression of amphiregulin in the basal epidermis is also associated with synovitis. Experimental Dermatology. 2004;13:347–356
- Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature. 2005;437:369–375
- Mutations in ANKH cause chondrocalcinosis. American Journal of Human Genetics. 2002;71:933–940
- . Biochemical and genetic analysis of ANK in arthritis and bone disease. American Journal of Human Genetics. 2006;79:1017–1029
- Melanocortin 3 receptors control crystal-induced inflammation. FASEB Journal. 2006;20:2234–2241
- . Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis & Rheumatism. 2002;46:2765–2775
- . Elucidation of Lyme arthritis. Nature Reviews. Immunology. 2004;4:143–152
- Distinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice. Infection and Immunity. 1998;66:161–168
- . Therapy for Lyme arthritis: strategies for the treatment of antibiotic-refractory arthritis. Arthritis & Rheumatism. 2006;54:3079–3086
PII: S1521-6942(08)00007-7
doi: 10.1016/j.berh.2008.01.007
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Best Practice & Research Clinical Rheumatology
Volume 22, Issue 2
, Pages 253-267
, April 2008
