Best Practice & Research Clinical Rheumatology
Volume 22, Issue 5 , Pages 831-845, October 2008

The antiphospholipid syndrome

Clinical Immunology Department, Nouvel Hopital Civil, Hopitaux Universitaires de Strasbourg, Université de Strasbourg and INSERM, U737, 67091 Strasbourg, France

The antiphospholipid syndrome is an acquired autoimmune syndrome characterized by arterial and/or venous thrombosis and/or pregnancy morbidity in association with the prolonged presence of serum autoantibodies, including the so-called lupus anticoagulant and anticardiolipin antibodies, which are mainly directed against complexes of proteins and anionic phospholipids.

Key words: anticardiolipin antibodies, antiphospholipid syndrome, lupus anticoagulant

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PII: S1521-6942(08)00097-1

doi:10.1016/j.berh.2008.08.008

Best Practice & Research Clinical Rheumatology
Volume 22, Issue 5 , Pages 831-845, October 2008

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