Best Practice & Research Clinical Rheumatology
Volume 23, Issue 4 , Pages 549-561, August 2009

Challenges of ethnicity in SLE

  • Kanta Kumar, BSc, Dip. RN (Rheumatology Clinical Research Nurse)

      Affiliations

    • Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, UK
    • Rheumatology Department, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham, UK
    • Corresponding Author InformationCorresponding author. Rheumatology Department, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham, B18 7QH, UK. Tel.: +44 121 507 5793; Fax: +44 121 507 5451.
  • ,
  • Sharon Chambers, MD, MRCP (Rheumatology Specialist Registrar)

      Affiliations

    • Department of Medicine, The Centre for Rheumatology, University College London, London, UK
  • ,
  • Caroline Gordon, MD, FRCP (Professor of Rheumatology)

      Affiliations

    • Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, UK
    • Rheumatology Department, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham, UK

Systemic lupus erythematosus (SLE) is associated with significant morbidity and mortality and has a huge impact on patients' well-being. The disease occurs worldwide and is particularly common in patients of African descent in Europe and North America and in those of Asian origin. Patients often require therapies for prolonged periods of time. The outcome of the disease is dependent on early diagnosis and treatment, and, most importantly, patients' willingness to accept the diagnosis and the need to adhere to advice about therapy. It is important to understand patients' beliefs and perceptions about the disease and its therapy, which are influenced by their ethnic background, as this is likely to influence adherence and outcome. Further research is required to identify the best approaches to improve patients' understanding about lupus and its treatments and to show that improving adherence does indeed improve long-term outcomes.

Keywords: SLE, adherence, beliefs, therapy, cultural, patient education

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PII: S1521-6942(09)00046-1

doi:10.1016/j.berh.2009.04.005

Best Practice & Research Clinical Rheumatology
Volume 23, Issue 4 , Pages 549-561, August 2009