« Previous
Next »
Best Practice & Research Clinical Rheumatology
Volume 23, Issue 5
, Pages 589-597
, October 2009
An overview of genetics of paediatric rheumatic diseases
References
- International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol. 2004 Feb;31(2):390–392
- Pediatric rheumatology in the United Kingdom: data from the British Pediatric Rheumatology Group National Diagnostic Register. J Rheumatol. 1996 Nov;23(11):1975–1980
- . Outcome following onset of juvenile idiopathic inflammatory arthritis: I. frequency of different outcomes. Rheumatology (Oxford). 2005 Aug;44(8):995–1001
- . Juvenile rheumatoid arthritis as a complex genetic trait. Arthritis Rheum. 1999 Nov;42(11):2261–2268
- Comparison of clinical and radiographic severity of juvenile-onset versus adult-onset ankylosing spondylitis. Ann Rheum Dis. 2008 Sep;9:
- Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients. Rheumatology (Oxford). 2002 Oct;41(10):1183–1189
- . A comprehensive review of the genetics of juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2008;6:11
- Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet. 2007 Nov;39(11):1329–1337
- Type 17T helper cells-origins, features and possible roles in rheumatic disease. Nat Rev Rheumatol. 2009 Jun;5(6):325–331
- A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006 Dec 1;314(5804):1461–1463
- A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet. 2007 Feb;80(2):273–290
- In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat Immunol. 2007 Jan;8(1):101–108
- Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. J Clin Invest. 2002 Aug;110(4):515–526
- . Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding. J Immunol. 2003 Dec 15;171(12):6814–6819
- . An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding. J Biol Chem. 2003 Aug 1;278(31):28677–28685
- . The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis. Rheumatology (Oxford). 2006 Apr;45(4):365–368
- Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis. Arthritis Rheum. 2009 Jan;60(1):251–257
- . Does systemic-onset juvenile idiopathic arthritis belong under juvenile idiopathic arthritis?. Rheumatology (Oxford). 2005 Nov;44(11):1350–1353
- . Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). Annu Rev Immunol. 2009;27:621–668
- The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: a multicenter study using simplex and multiplex juvenile idiopathic arthritis families. Arthritis Rheum. 2003 Nov;48(11):3202–3206
- Specific gene expression profiles in systemic juvenile idiopathic arthritis. Arthritis Rheum. 2007 Jun;56(6):1954–1965
- Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis. Arthritis Rheum. 2009 Jul;60(7):2102–2112
- Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007 Jun 7;447(7145):661–678
- Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis. Arthritis Rheum. 2009 Jan;60(1):258–263
- A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage. Arthritis Rheum. 2004 Sep;50(9):2920–2930
- . Pathways to gene identification in rheumatoid arthritis: PTPN22 and beyond. Immunol Rev. 2005 Apr;204:74–86
- Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. J Exp Med. 2007 Sep 3;204(9):2131–2144
- Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum. 2007 Nov;56(11):3793–3804
- Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms. Arthritis Rheum. 2008 Sep;58(9):2892–2896
- Hunter P, Nistala K, Jina N, et al. Biological predictors of extension of oligoarticular juvenile idiopathic arthritis from synovial fluid cellular composition and gene expression. Arthritis Rheum (in press).
- Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum. 2009 Jul;60(7):2113–2123
- . Pathogenesis of ankylosing spondylitis: current concepts. Best Pract Res Clin Rheumatol. 2006 Jun;20(3):571–591
- CD8 alpha beta T cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats. J Immunol. 2003 Jan 15;170(2):1099–1105
- Spondylarthritis in HLA-B27/human beta(2)-microglobulin-transgenic rats is not prevented by lack of CD8. Arthritis Rheum. 2009 Jul;60(7):1977–1984
- HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheum. 2007 Jan;56(1):215–223
- . HLA-B27 misfolding and the unfolded protein response augment IL-23 production and are associated with Th17 activation in transgenic rats. Arthritis Rheum. 2009;60:2633–2643
- . Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003 Mar;33(Suppl.):245–254
- The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias. Mol Cancer. 2009;8:42
- . The genetics and epigenetics of autoimmune diseases. J Autoimmun. 2009 Aug;33(1):3–11
- Treating activated CD4
+
T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. J Clin Invest. 1993 Jul;92(1):38–53 - Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. J Immunol. 1995 Mar 15;154(6):3025–3035
- Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. J Immunol. 1988 Apr 1;140(7):2197–2200
- . Maternal transmission of diabetes. Diabet Med. 2002 Feb;19(2):89–98
- Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum. 1990 Nov;33(11):1665–1673
- . Silencing of CD21 expression in synovial lymphocytes is independent of methylation of the CD21 promoter CpG island. Rheumatol Int. 2001 May;20(4):133–137
- . Epigenetic control of T-helper-cell differentiation. Nat Rev Immunol. 2009 Feb;9(2):91–105
- . MicroRNA signatures in human cancers. Nat Rev Cancer. 2006 Nov;6(11):857–866
- Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther. 2008;10(4):R101
- Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum. 2008 Apr;58(4):1001–1009
PII: S1521-6942(09)00081-3
doi: 10.1016/j.berh.2009.08.001
© 2009 Elsevier Ltd. All rights reserved.
« Previous
Next »
Best Practice & Research Clinical Rheumatology
Volume 23, Issue 5
, Pages 589-597
, October 2009
