Best Practice & Research Clinical Rheumatology
Volume 24, Issue 1 , Pages 39-46 , February 2010

The role of biomechanics in the initiation and progression of OA of the knee

  • Martin Englund, MD, PhD (Epidemiologist)

      Affiliations

    • Musculoskeletal Sciences, Department of Orthopedics, Clinical Sciences Lund, Lund University, Sweden
    • Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, USA
    • Corresponding Author InformationMusculoskeletal Sciences, Department of Orthopedics, Clinical Sciences Lund, Lund University, Hospital, Klinikgatan 22, SE-221 85 Lund, Sweden. Tel.:+46 46 171394, Fax: +46 46 177167.

References 

  1. Lopez AD, Mathers CD, Ezzati M, et al. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet. 2006 May 27;367(9524):1747–1757
  2. Owman H, Tiderius CJ, Neuman P, et al. Association between findings on delayed gadolinium-enhanced magnetic resonance imaging of cartilage and future knee osteoarthritis. Arthritis Rheum. 2008 Jun;58(6):1727–1730
  3. Williams A, Gillis A, McKenzie C, et al. Glycosaminoglycan distribution in cartilage as determined by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC): potential clinical applications. AJR Am J Roentgenol. 2004 Jan;182(1):167–172
  4. Day B, Mackenzie WG, Shim SS, Leung G. The vascular and nerve supply of the human meniscus. Arthroscopy. 1985;1(1):58–62
  5. Arnoczky SP, Warren RF. Microvasculature of the human meniscus. Am J Sports Med. 1982 Mar-Apr;10(2):90–95
  6. Seedhom BB, Hargreaves DJ. Transmission of the load in the knee joint with special reference to the role of the meniscus. Part I+II. Eng Med. 1979;4:207–228
  7. Walker PS, Erkman MJ. The role of the menisci in force transmission across the knee. Clin Orthop. 1975;184–192109
  8. Kurosawa H, Fukubayashi T, Nakajima H. Load-bearing mode of the knee joint: physical behavior of the knee joint with or without menisci. Clin Orthop. 1980 Jun;283–290149
  9. Levangie PK, Norkin CC. Joint structure and function. A comprehensive analysis. Philadelphia: F.A. Davis Company; 2005;
  10. Hunter DJ, Zhang Y, Niu J, et al. Structural factors associated with malalignment in knee osteoarthritis: the Boston osteoarthritis knee study. J Rheumatol. 2005 Nov;32(11):2192–2199
  11. Kraus VB, Vail TP, Worrell T, McDaniel G. A comparative assessment of alignment angle of the knee by radiographic and physical examination methods. Arthritis Rheum. 2005 Jun;52(6):1730–1735
  12. Chang A, Hayes K, Dunlop D, et al. Thrust during ambulation and the progression of knee osteoarthritis. Arthritis Rheum. 2004 Dec;50(12):3897–3903
  13. Sharma L, Song J, Felson DT, et al. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. J Am Med Assoc. 2001 Jul 11;286(2):188–195
  14. Sharma L, Eckstein F, Song J, et al. Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees. Arthritis Rheum. 2008 Jun;58(6):1716–1726
  15. Hunter DJ, Niu J, Felson DT, et al. Knee alignment does not predict incident osteoarthritis: the framingham osteoarthritis study. Arthritis Rheum. 2007 Apr;56(4):1212–1218
  16. Brouwer RW, Raaij van TM, Bierma-Zeinstra SMA, et al. Osteotomy for treating knee osteoarthritis. Cochrane Database Syst Rev. 2007;
  17. Annandale T. An operation for displaced semilunar cartilage. Br Med J. 1885;1:779
  18. Annandale T. Excision of the internal semilunar cartilage, resulting in perfect restoration of the joint movements. Br Med J. 1889;1:291–292
  19. Fairbank TJ. Knee joint changes after meniscectomy. J Bone Joint Surg Br. 1948;30:164–170
  20. Gear MW. The late results of meniscectomy. Br J Surg. 1967 Apr;54(4):270–272
  21. Tapper EM, Hoover NW. Late results after meniscectomy. J Bone Joint Surg Am. 1969 Apr;51(3):517–526
  22. Johnson RJ, Kettelkamp DB, Clark W, Leaverton P. Factors effecting late results after meniscectomy. J Bone Joint Surg Am. 1974 Jun;56(4):719–729
  23. Noble J. Clinical features of the degenerate meniscus with the results of meniscectomy. Br J Surg. 1975 Dec;62(12):977–981
  24. Noble J, Erat K. In defence of the meniscus. A prospective study of 200 meniscectomy patients. J Bone Joint Surg Br. 1980 Feb;62-B(1):7–11
  25. Sonne-Holm S, Fledelius I, Ahn NC. Results after meniscectomy in 147 athletes. Acta Orthop Scand. 1980 Apr;51(2):303–309
  26. Doherty M, Watt I, Dieppe P. Influence of primary generalised osteoarthritis on development of secondary osteoarthritis. Lancet. 1983 Jul 2;2(8340):8–11
  27. Allen PR, Denham RA, Swan AV. Late degenerative changes after meniscectomy. Factors affecting the knee after operation. J Bone Joint Surg Br. 1984 Nov;66(5):666–671
  28. Jørgensen U, Sonne-Holm S, Lauridsen F, Rosenklint A. Long-term follow-up of meniscectomy in athletes. A prospective longitudinal study. J Bone Joint Surg Br. 1987 Jan;69(1):80–83
  29. Roos H, Lauren M, Adalberth T, et al. Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum. 1998 Apr;41(4):687–693
  30. Englund M, Lohmander LS. Risk factors for symptomatic knee osteoarthritis fifteen to twenty-two years after meniscectomy. Arthritis Rheum. 2004;50(9):2811–2819
  31. Shrive NG, O'Connor JJ, Goodfellow JW. Load-bearing in the knee joint. Clin Orthop. 1978 Mar-Apr;279–287131
  32. Fukubayashi T, Kurosawa H. The contact area and pressure distribution pattern of the knee. A study of normal and osteoarthritic knee joints. Acta Orthop Scand. 1980 Dec;51(6):871–879
  33. Steenbrugge F, Verdonk R, Verstraete K, et al. Long-term assessment of arthroscopic meniscus repair: a 13-year follow-up study. Knee. 2002;9(3):181–187
  34. Rockborn P, Messner K. Long-term results of meniscus repair and meniscectomy: a 13-year functional and radiographic follow-up study. Knee Surg Sports Traumatol Arthrosc. 2000;8(1):2–10
  35. Hall MJ, Lawrence L. Ambulatory surgery in the United States, 1996. Hyattsville, Maryland: U.S. Department of Health and Human Service, Centers for Disease Control and Prevention, National Center for Health Statistics; 1998 August 12;Report No.: 300
  36. Hede A, Larsen E, Sandberg H. The long term outcome of open total and partial meniscectomy related to the quantity and site of the meniscus removed. Int Orthop. 1992;16(2):122–125
  37. Poehling GG, Ruch DS, Chabon SJ. The landscape of meniscal injuries. Clin Sports Med. 1990 Jul;9(3):539–549
  38. Noble J, Hamblen DL. The pathology of the degenerate meniscus lesion. J Bone Joint Surg Br. 1975 May;57(2):180–186
  39. Noble J. Lesions of the menisci. Autopsy incidence in adults less than fifty-five years old. J Bone Joint Surg Am. 1977 Jun;59(4):480–483
  40. Smillie IS. Surgical pathology of the Menisci. Injuries of the knee joint. 3rd ed.. Baltimore: The Williams and Wilkins Co.; 1962;pp. 51–90
  41. Englund M, Guermazi A, Gale D, et al. Incidental meniscal findings on knee MRI in middle-aged and elderly persons. N Engl J Med. 2008 Sep 11;359(11):1108–1115
  42. Englund M, Guermazi A, Roemer FW, et al. Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: the multicenter osteoarthritis study. Arthritis Rheum. 2009 Mar;60(3):831–839
  43. Adams JG, McAlindon T, Dimasi M, et al. Contribution of meniscal extrusion and cartilage loss to joint space narrowing in osteoarthritis. Clin Radiol. 1999 Aug;54(8):502–506
  44. Gale DR, Chaisson CE, Totterman SM, et al. Meniscal subluxation: association with osteoarthritis and joint space narrowing. Osteoarthritis Cartilage. 1999 Nov;7(6):526–532
  45. Berthiaume MJ, Raynauld JP, Martel-Pelletier J, et al. Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis. 2005 Apr;64(4):556–563
  46. Ding C, Martel-Pelletier J, Pelletier JP, et al. Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume. Arthritis Res Ther. 2007;9(2):R21
  47. Hunter DJ, Zhang YQ, Niu JB, et al. The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum. 2006 Mar;54(3):795–801
  48. Lohmander LS, Englund PM, Dahl LL, Roos EM. The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med. 2007 Oct;35(10):1756–1769
  49. Buckwalter JA. Articular cartilage injuries. Clin Orthop Relat Res. 2002 Sep;21–37402
  50. Neuman P, Englund M, Kostogiannis I, et al. Prevalence of tibiofemoral osteoarthritis 15 years after nonoperative treatment of anterior cruciate ligament injury: a prospective cohort study. Am J Sports Med. 2008 Sep;36(9):1717–1725
  51. Marx RG, Jones EC, Angel M, et al. Beliefs and attitudes of members of the American Academy of Orthopaedic surgeons regarding the treatment of anterior cruciate ligament injury. Arthroscopy. 2003 Sep;19(7):762–770
  52. Spindler KP, Wright RW. Clinical practice. Anterior cruciate ligament tear. N Engl J Med. 2008 Nov 13;359(20):2135–2142
  53. Anderson JJ, Felson DT. Factors associated with osteoarthritis of the knee in the first national Health and Nutrition Examination Survey (HANES I). Evidence for an association with overweight, race, and physical demands of work. Am J Epidemiol. 1988 Jul;128(1):179–189
  54. McAlindon TE, Wilson PW, Aliabadi P, et al. Level of physical activity and the risk of radiographic and symptomatic knee osteoarthritis in the elderly: the Framingham study. Am J Med. 1999 Feb;106(2):151–157
  55. Felson DT, Zhang Y, Hannan MT, et al. Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study. Arthritis Rheum. 1997 Apr;40(4):728–733
  56. Cheng Y, Macera CA, Davis DR, et al. Physical activity and self-reported, physician-diagnosed osteoarthritis: is physical activity a risk factor?. J Clin Epidemiol. 2000 Mar 1;53(3):315–322
  57. Jensen LK, Mikkelsen S, Loft IP, et al. Radiographic knee osteoarthritis in floorlayers and carpenters. Scand J Work Environ Health. 2000 Jun;26(3):257–262
  58. Zhang Y, Hunter DJ, Nevitt MC, et al. Association of squatting with increased prevalence of radiographic tibiofemoral knee osteoarthritis: the Beijing Osteoarthritis Study. Arthritis Rheum. 2004 Apr;50(4):1187–1192
  59. Amin S, Goggins J, Niu J, et al. Occupation-related squatting, kneeling, and heavy lifting and the knee joint: a magnetic resonance imaging-based study in men. J Rheumatol. 2008 Aug;35(8):1645–1649
  60. Rytter S, Jensen LK, Bonde JP, et al. Occupational kneeling and meniscal tears: a magnetic resonance imaging study in floor layers. J Rheumatol. 2009 Jul;36(7):1512–1519
  61. Felson DT, Anderson JJ, Naimark A, et al. Obesity and knee osteoarthritis. The Framingham Study. Ann Intern Med. 1988 Jul 1;109(1):18–24
  62. Spector TD, Hart DJ, Doyle DV. Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity. Ann Rheum Dis. 1994 Sep;53(9):565–568
  63. Hochberg MC, Lethbridge-Cejku M, Scott WW, et al. The association of body weight, body fatness and body fat distribution with osteoarthritis of the knee: data from the Baltimore Longitudinal Study of Aging. J Rheumatol. 1995 Mar;22(3):488–493
  64. Gelber AC, Hochberg MC, Mead LA, et al. Body mass index in young men and the risk of subsequent knee and hip osteoarthritis. Am J Med. 1999 Dec;107(6):542–548
  65. Niu J, Zhang YQ, Torner J, et al. Is obesity a risk factor for progressive radiographic knee osteoarthritis?. Arthritis Rheum. 2009 Mar 15;61(3):329–335
  66. Hotamisligil GS. Inflammation and metabolic disorders. Nature. 2006 Dec 14;444(7121):860–867

PII: S1521-6942(09)00085-0

doi: 10.1016/j.berh.2009.08.008

Best Practice & Research Clinical Rheumatology
Volume 24, Issue 1 , Pages 39-46 , February 2010

Article Tools

* Image Usage & Resolution